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Literature summary extracted from

  • Lavaissiere, L.; Jia, S.; Nishiyama, M.; de la Monte, S.; Stern, A.M.; Wands, J.R.; Friedman, P.A.
    Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma (1996), J. Clin. Invest., 98, 1313-1323.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.16 Homo sapiens
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.11.16 adrenal gland
-
 Homo sapiens
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1.14.11.16 breast cancer cell highly expressed Homo sapiens
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1.14.11.16 cholangiocarcinoma cell highly expressed in all cholangiocarcinomas Homo sapiens
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1.14.11.16 colonic carcinoma cell highly expressed Homo sapiens
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1.14.11.16 hepatoma cell highly expressed in 4 of 10 hepatocarcinomas, 10-fold activity increase Homo sapiens
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1.14.11.16 liver
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 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.16 peptide L-asparagine + 2-oxoglutarate + O2 first epidermal growth factor-like domain of bovine protein S with an asparagine replacing the aspartic acid at position 18 Homo sapiens peptide 3-hydroxy-L-asparagine + succinate + CO2
-
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