EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.11.4 | expression in insect cells using a baculovirus vector | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.11.4 | malaoxon | mechanism of inhibition | Rattus norvegicus | |
1.14.11.4 | malathion | mechanism of inhibition | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.11.4 | 85000 | - |
x * 85000, SDS-PAGE and Western blotting | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.4 | collagen + 2-oxoglutarate + O2 | Rattus norvegicus | enzyme required during collagen biosynthesis | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? | |
1.14.11.4 | collagen + 2-oxoglutarate + O2 | Rattus norvegicus | influence the integrity and stability of collagen | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.11.4 | Rattus norvegicus | Q63321 | - |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
1.14.11.4 | side-chain modification | hydroxylation of lysyl residue in -X-Lys-Gly | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.11.4 | collagen + 2-oxoglutarate + O2 | enzyme required during collagen biosynthesis | Rattus norvegicus | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? | |
1.14.11.4 | collagen + 2-oxoglutarate + O2 | influence the integrity and stability of collagen | Rattus norvegicus | 5-hydroxylysyl-collagen + succinate + CO2 | - |
? | |
1.14.11.4 | peptidyl-L-lysine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | peptidyl-5-hydroxy-L-lysine + succinate + CO2 | hydroxy-L-lysine | ? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.11.4 | ? | x * 85000, SDS-PAGE and Western blotting | Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.11.4 | 0.047 | - |
malaoxon | - |
Rattus norvegicus | |
1.14.11.4 | 0.059 | - |
malathion | - |
Rattus norvegicus |