Literature summary extracted from

Kumar, R.P.; Ravindranath, S.D.; Vaidyanathan, C.S.; Rao, N.A.
Mechanism of hydroxylation of aromatic compounds. II. Evidence for the involvement of superoxide anions in enzymatic hydroxylations (1972), Biochem. Biophys. Res. Commun., 49, 1422-1426.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.13.35	additional information	complete inhibition when superoxide dismutase is included in the reaction mixture for the assay of the enzyme	Aspergillus niger

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.13.35	Aspergillus niger	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
1.14.13.35	anthranilate + NADPH + H+ + O2 = 2,3-dihydroxybenzoate + NADP+ + NH3	possible involvement of superoxide anion (O2-) in the reaction	Aspergillus niger	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.13.35	anthranilate + NADPH + O2	-	Aspergillus niger	2,3-dihydroxybenzoate + NADP+ + NH3	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.14.13.35	NADPH	-	Aspergillus niger

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Release 2023.1 (January 2023)