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Literature summary extracted from

  • Soodsma, J.F.; Piantadosi, C.; Snyder, F.
    Partial characterization of the alkylglycerol cleavage enzyme system of rat liver (1972), J. Biol. Chem., 247, 3923-3929.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.16.5 (NH4)2SO4 activates, optimal concentration is 1.25 mM Rattus norvegicus
1.14.16.5 GSH 10 mM, increase reaction 5fold Rattus norvegicus
1.14.16.5 NH4Cl activates Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.16.5 (NH4)2Mo7O24
-
 Rattus norvegicus
1.14.16.5 CaCl2
-
 Rattus norvegicus
1.14.16.5 CsCl
-
 Rattus norvegicus
1.14.16.5 KCl
-
 Rattus norvegicus
1.14.16.5 MgSO4
-
 Rattus norvegicus
1.14.16.5 MnCl2
-
 Rattus norvegicus
1.14.16.5 NaCl
-
 Rattus norvegicus
1.14.16.5 ZnCl2
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.16.5 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.16.5 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.16.5 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.16.5 hexadecylglycerol + tetrahydrobiopterin + O2
-
 Rattus norvegicus hexadecanal + glycerol + dihydrobiopterin + H2O
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.16.5 9
-
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.16.5 NAD+ stimulates Rattus norvegicus
1.14.16.5 NADH stimulates Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.14.16.5 0.32
-
 hexadecyl-L-alpha-lyso-phosphatidylcholine
-
 Rattus norvegicus