EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.17.1 | beta-Ethynyltyramine | and enantiomers, mechanism of inhibition | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.17.1 | 3,4-dihydroxyphenethylamine + ascorbate + O2 | Bos taurus | enzyme plays a key role in the biosynthetic interconversion of neurotransmitters | noradrenaline + dehydroascorbate + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.17.1 | Bos taurus | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.14.17.1 | dopamine + 2 ascorbate + O2 = noradrenaline + 2 monodehydroascorbate + H2O | mechanism | Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.17.1 | adrenal medulla | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.17.1 | 3,4-dihydroxyphenethylamine + ascorbate + O2 | - |
Bos taurus | noradrenaline + dehydroascorbate + H2O | norepinephrine | ? | |
1.14.17.1 | 3,4-dihydroxyphenethylamine + ascorbate + O2 | enzyme plays a key role in the biosynthetic interconversion of neurotransmitters | Bos taurus | noradrenaline + dehydroascorbate + H2O | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.17.1 | 0.015 | - |
beta-ethynytyramine | R,S-1 | Bos taurus | |
1.14.17.1 | 0.057 | - |
beta-ethynytyramine | S-1, in the presence of ascorbate | Bos taurus | |
1.14.17.1 | 0.208 | - |
beta-ethynytyramine | S-1 | Bos taurus |