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Literature summary extracted from

  • Colombo, G.; Papadopoulos, N.J.; Ash, D.E.; Villafranca, J.J.
    Characterization of highly purified dopamine beta-hydroxylase (1987), Arch. Biochem. Biophys., 252, 71-80.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.17.1 ascorbate
-
 Bos taurus
1.14.17.1 malonate
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.17.1 chromaffin granule
-
 Bos taurus 42583
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.17.1 Cu2+ a copper protein Bos taurus
1.14.17.1 Cu2+ about 8 Cu2+ per tetramer Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.17.1 3,4-dihydroxyphenethylamine + ascorbate + O2 Bos taurus
-
 noradrenaline + dehydroascorbate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.17.1 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.17.1
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.17.1 adrenal medulla
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.17.1 69
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.17.1 3,4-dihydroxyphenethylamine + ascorbate + O2
-
 Bos taurus noradrenaline + dehydroascorbate + H2O
-
 ?
1.14.17.1 3,4-dihydroxyphenethylamine + ascorbate + O2
-
 Bos taurus noradrenaline + dehydroascorbate + H2O norepinephrine ?