BRENDA - Enzyme Database

Characterization of highly purified dopamine beta-hydroxylase

Colombo, G.; Papadopoulos, N.J.; Ash, D.E.; Villafranca, J.J.; Arch. Biochem. Biophys. 252, 71-80 (1987)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.14.17.1
ascorbate
-
Bos taurus
1.14.17.1
malonate
-
Bos taurus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.17.1
chromaffin granule
-
Bos taurus
42583
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.14.17.1
Cu2+
about 8 Cu2+ per tetramer; a copper protein
Bos taurus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
Bos taurus
-
noradrenaline + dehydroascorbate + H2O
-
Bos taurus
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.14.17.1
Bos taurus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
1.14.17.1
-
Bos taurus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.17.1
adrenal medulla
-
Bos taurus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.14.17.1
69
-
-
Bos taurus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
-
438601
Bos taurus
noradrenaline + dehydroascorbate + H2O
-
438601
Bos taurus
?
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
-
438601
Bos taurus
noradrenaline + dehydroascorbate + H2O
norepinephrine
438601
Bos taurus
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.14.17.1
ascorbate
-
Bos taurus
1.14.17.1
malonate
-
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.14.17.1
chromaffin granule
-
Bos taurus
42583
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.14.17.1
Cu2+
about 8 Cu2+ per tetramer; a copper protein
Bos taurus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
Bos taurus
-
noradrenaline + dehydroascorbate + H2O
-
Bos taurus
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.14.17.1
-
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.14.17.1
adrenal medulla
-
Bos taurus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.14.17.1
69
-
-
Bos taurus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
-
438601
Bos taurus
noradrenaline + dehydroascorbate + H2O
-
438601
Bos taurus
?
1.14.17.1
3,4-dihydroxyphenethylamine + ascorbate + O2
-
438601
Bos taurus
noradrenaline + dehydroascorbate + H2O
norepinephrine
438601
Bos taurus
?