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Literature summary extracted from

  • Hulcher, F.H.
    Modification of the radiochemical assay of rat liver mevalonate-5-diphosphate decarboxylase and induction and stabilization of the activity (1991), Biochem. Biophys. Res. Commun., 181, 1449-1455.
    View publication on PubMed

General Stability

EC Number General Stability Organism
4.1.1.33 stabilized by phenylmethylsulfonyl fluoride, aprotinin and leupeptin Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.33 ATP + 5-diphosphomevalonate Rattus norvegicus enzyme activity is increased by 5fold after feeding young rats 2.5% cholestyramine for ten days to four weeks ADP + phosphate + isopentenyl diphosphate + CO2
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 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.33 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.33 liver
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 Rattus norvegicus
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Storage Stability

EC Number Storage Stability Organism
4.1.1.33 -20°C or -73°C, rat liver homogenate with 0.1 mM leupeptin, 0.75 mg/l aprotinin, 0.1 mM phenylmethylsulfonyl fluoride, 15 mM EDTA, 15 mM EGTA, stable for over 3 months Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.33 ATP + 5-diphosphomevalonate
-
 Rattus norvegicus ADP + phosphate + isopentenyl diphosphate + CO2
-
 ?
4.1.1.33 ATP + 5-diphosphomevalonate enzyme activity is increased by 5fold after feeding young rats 2.5% cholestyramine for ten days to four weeks Rattus norvegicus ADP + phosphate + isopentenyl diphosphate + CO2
-
 ?