Literature summary extracted from

Jabalquinto, A.M.; Cardemil, E.
Substrate binding order in mevalonate 5-diphosphate decarboxylase from chicken liver (1989), Biochim. Biophys. Acta, 996, 257-259.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.1.1.33	adenosine 5'-O-(3-thiotriphosphate)	-	Gallus gallus
4.1.1.33	mevalonate	mixed inhibition	Gallus gallus
4.1.1.33	mevalonate 5-phosphate	mixed inhibition	Gallus gallus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.33	Gallus gallus	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
4.1.1.33	ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2	ordered sequential mechanism with mevalonate 5-diphosphate as the first substrate to bind to the enzyme	Gallus gallus	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.33	ATP + 5-diphosphomevalonate	-	Gallus gallus	ADP + phosphate + isopentenyl diphosphate + CO2	-	?

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Release 2023.1 (January 2023)