EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.99.1 | 5-bromo-2-[4-fluorophenyl]-3-[4-methylsulfonylphenyl]-thiophene | DuP-697, selective for isozyme 2 | Homo sapiens | |
1.14.99.1 | Ibuprofen | reversible | Homo sapiens | |
1.14.99.1 | indomethacin | reversible and time-dependent inhibition | Homo sapiens | |
1.14.99.1 | additional information | mechanism of selective inhibition | Homo sapiens | |
1.14.99.1 | N-[2-cyclohexyloxy-4-nitrophenyl]methanesulfonamide | NS-398, selective for isozyme 2 | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.99.1 | 0.001 | - |
arachidonic acid | isozyme 1 and 2 | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.99.1 | Homo sapiens | - |
recombinant enzyme, product of COX-2 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.99.1 | arachidonate + electron donor + O2 | - |
Homo sapiens | prostaglandin H2 + oxidized electron donor + H2O | - |
? |