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Literature summary extracted from
- Comparison of two monooxygenase systems with cytochrome P450 in filamentous fungus Rhizopus nigricans (2000), Pflugers Arch., 439, R107-108.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.99.14 | ketoconazole | - |
Rhizopus stolonifer |  |
| 1.14.99.14 | Metyrapone | - |
Rhizopus stolonifer | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.99.14 | membrane | - |
Rhizopus stolonifer | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.99.14 | progesterone + NADPH + O2 | Rhizopus stolonifer | multicomponent monooxygenase system | 11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.99.14 | Rhizopus stolonifer | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.99.14 | progesterone + NADPH + O2 | - |
Rhizopus stolonifer | 11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
| 1.14.99.14 | progesterone + NADPH + O2 | multicomponent monooxygenase system | Rhizopus stolonifer | 11alpha-hydroxyprogesterone + NADP+ + H2O | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.99.14 | cytochrome P450 | - |
Rhizopus stolonifer |
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Release 2023.1 (January 2023)
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