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Literature summary extracted from

  • Yan, W.; Jang, G.F.; Haeseleer, F.; Esumi, N.; Chang, J.; Kerrigan, M.; Campochiaro, M.; Campochiaro, P.; Palczewski, K.; Zack, D.J.
    Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium (2001), Genomics, 72, 193-202.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.63 baculovurus expressed Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.63 beta-carotene + O2 Homo sapiens enzyme plays an important role in retinoid synthesis. BCDO may also be a candidate gene for retinal degenerative disease retinal
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.63 Homo sapiens Q9HAY6
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-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.63 brain
-
 Homo sapiens
-
1.13.11.63 kidney
-
 Homo sapiens
-
1.13.11.63 liver
-
 Homo sapiens
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1.13.11.63 retina enzyme is highly expressed in retinal pigment epithelium Homo sapiens
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1.13.11.63 stomach
-
 Homo sapiens
-
1.13.11.63 testis
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.63 beta-carotene + O2 enzyme plays an important role in retinoid synthesis. BCDO may also be a candidate gene for retinal degenerative disease Homo sapiens retinal
-
 ?