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Literature summary extracted from

  • Salin, M.L.; Day, E.D.; Crapo, J.D.
    Isolation and characterization of a manganese-containing superoxide dismutase from rat liver (1978), Arch. Biochem. Biophys., 187, 223-228.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.15.1.1 1 cycle of freezing and thawing causes 30% loss of activity Rattus norvegicus
1.15.1.1 freezing causes rapid deterioation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.15.1.1 CN- Cu,Zn-SOD; no inhibition Mn-SOD Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.15.1.1 Mn2+ 3.69 mol per mol of enzyme Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.15.1.1 22400
-
 4 * 22400, Mn-SOD, SDS-PAGE Rattus norvegicus
1.15.1.1 89000
-
 sedimentation equilibrium analysis Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.15.1.1 Rattus norvegicus
-
 Mn-SOD
-
1.15.1.1 Rattus norvegicus Mn-SOD
-
 Mn-SOD
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.15.1.1 Mn-SOD Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.15.1.1 liver Mn-SOD Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.15.1.1 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.15.1.1 O2- + H+
-
 Rattus norvegicus O2 + H2O2
-
 ?
1.15.1.1 O2- + H+
-
 Rattus norvegicus Mn-SOD O2 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.15.1.1 tetramer 4 * 22400, Mn-SOD, SDS-PAGE Rattus norvegicus