Literature summary extracted from

Hamann, C.S.; Lentainge, S.; Li, L.S.; Salem, J.S.; Yang, F.D.; Cooperman, B.S.
Chimeric small subunit inhibitors of mammalian ribonucleotide reductase: a dual function for the R2 C-terminus? (1998), Protein Eng., 11, 219-224.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.17.4.1	expression of chimeric R2 genes in which C-terminal sequences in Escherichia coli subunit R2 are replaced by C-terminal sequences from the mouse subunit R2	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.17.4.1	Escherichia coli	-	-	-
1.17.4.1	Mus musculus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.17.4.1	chimeric R2 genes in which C-terminal sequences in Escherichia coli subunit R2 are replaced by C-terminal sequences from the mouse subunit R2	Mus musculus
1.17.4.1	chimeric R2 genes in which C-terminal sequences in Escherichia coli subunit R2 are replaced by C-terminal sequences from the mouse subunit R2	Escherichia coli

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.17.4.1	ribonucleoside diphosphate + reduced thioredoxin	-	Mus musculus	2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O	-	ir
1.17.4.1	ribonucleoside diphosphate + reduced thioredoxin	-	Escherichia coli	2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O	-	ir

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Release 2023.1 (January 2023)