EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.1 | Iron | iron center stabilizes tyrosyl radical, distance between the iron center and the tyrosyl radical is estimated to be 6-9.0 A | Escherichia coli | |
1.17.4.1 | Iron | iron binds directly to the enzyme structure and not via sulfur | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.1 | Escherichia coli | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.17.4.1 | 2'-deoxyribonucleoside 5'-diphosphate + thioredoxin disulfide + H2O = ribonucleoside 5'-diphosphate + thioredoxin | proposed mechanism | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.17.4.1 | More | tyrosyl radical is stabilized by an iron center | Escherichia coli |
1.17.4.1 | More | the active form of B2 subunit contains a tyrosyl radical essential for activity | Escherichia coli |