EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.1 | additional information | L1210 cells with resistance to specific nucleotide reductase inhibitors | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.1 | Mus musculus | - |
wild-type and reductase inhibitor resistant L1210 cell line | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.17.4.1 | L-1210 cell | L1210 cells resistant to specific ribonucleotide reductase inhibitors | Mus musculus | - |
1.17.4.1 | L-cell | cell line | Mus musculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.17.4.1 | additional information | - |
extracts from hydroxyurea resistant cell line HU-7 exhibit a 13fold higher ADP reductase activity and a 5fold higher CDP reductase activity when compared to wild-type | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.1 | ribonucleoside diphosphate + reduced thioredoxin | - |
Mus musculus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir |