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Literature summary extracted from

  • MacKenzie, D.A.; Carter, A.T.; Wongwathanarat, P.; Eagles, J.; Salt, J.; Archer, D.B.
    A third fatty acid DELTA9-desaturase from Mortierella alpina with a different substrate specificity to ole1p and ole2p (2002), Microbiology, 148, 1725-1735.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.1 expression of DELTA9-3 gene in Saccharomyces cerevisiae Mortierella alpina

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.19.1 endoplasmic reticulum
-
 Mortierella alpina 5783
-
1.14.19.1 membrane bound Mortierella alpina 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.1 additional information Mortierella alpina long-chain polyunsaturated fatty acid biosynthetic pathway ?
-
 ?
1.14.19.1 additional information Mortierella alpina CBS 528.72 / ATCC 32222 long-chain polyunsaturated fatty acid biosynthetic pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.1 Mortierella alpina
-
-
-
1.14.19.1 Mortierella alpina CBS 528.72 / ATCC 32222
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.19.1 stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O isolation of a third fatty acid DELTA9-desaturase. Higher activity with longer chain fatty acid substrates. Desaturase expression is induced significantly by increasing the ratio of carbon to nitrogen Mortierella alpina
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.1 additional information long-chain polyunsaturated fatty acid biosynthetic pathway Mortierella alpina ?
-
 ?
1.14.19.1 additional information long-chain polyunsaturated fatty acid biosynthetic pathway Mortierella alpina CBS 528.72 / ATCC 32222 ?
-
 ?
1.14.19.1 palmitic acid + AH2 + O2
-
 Mortierella alpina palmitoleic acid + A + H2O
-
 ?
1.14.19.1 palmitic acid + AH2 + O2
-
 Mortierella alpina CBS 528.72 / ATCC 32222 palmitoleic acid + A + H2O
-
 ?
1.14.19.1 stearate + AH2 + O2
-
 Mortierella alpina oleate + A + 2 H2O
-
 ?
1.14.19.1 stearate + AH2 + O2
-
 Mortierella alpina CBS 528.72 / ATCC 32222 oleate + A + 2 H2O
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.1 cytochrome b5 fusion, C-terminal Mortierella alpina