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Literature summary extracted from
- The effect of diabetes, nutritional factors, and sex on rat liver and kidney mevalonate kinase, mevalonate-5-phosphate kinase, and mevalonate-5-pyrophosphate decarboxylase (1981), Arch. Biochem. Biophys., 210, 132-139.
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.33 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.33 | kidney | in female rat the activity is lower than in male rat | Rattus norvegicus | - |
| 4.1.1.33 | liver | in female rats the activity is higher than in male animals | Rattus norvegicus | - |
| 4.1.1.33 | liver | decrease in activity when rats are fasted, fed with a diet containing 2% cholesterol or made diabetic, increase in activity when the animals are fed with a diet containing 3% cholestyramine | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.33 | ATP + 5-diphosphomevalonate | - |
Rattus norvegicus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
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