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Literature summary extracted from

  • Dimroth, P.; Thomer, A.
    Kinetic analysis of the reaction mechanism of oxaloacetate decarboxylase from Klebsiella aerogenes (1986), Eur. J. Biochem., 156, 157-162.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.4.2 2-Oxomalonate Ki: 0.06 mM Klebsiella aerogenes
7.2.4.2 glyoxylate Ki: 0.04 mM Klebsiella aerogenes
7.2.4.2 oxalate Ki: 0.0035 Klebsiella aerogenes
7.2.4.2 pyruvate product inhibition competitive for oxaloacetate, Ki: 1.3 mM, noncompetitive inhibition for Na+, Ki: 2 mM Klebsiella aerogenes

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.4.2 membrane
-
Klebsiella aerogenes 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.2.4.2 Li+ Km: 25 mM Klebsiella aerogenes
7.2.4.2 Na+ Km: 1.5 mM Klebsiella aerogenes

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.4.2 oxaloacetate Klebsiella aerogenes
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.2.4.2 Klebsiella aerogenes
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.4.2 additional information transmembrane transport of Na+ Klebsiella aerogenes ?
-
?
7.2.4.2 Oxaloacetate reaction mechanism Klebsiella aerogenes Pyruvate + CO2
-
?
7.2.4.2 oxaloacetate
-
Klebsiella aerogenes ?
-
?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
7.2.4.2 50
-
only if protected by oxalate Klebsiella aerogenes

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
7.2.4.2 0.0035
-
oxalate
-
Klebsiella aerogenes
7.2.4.2 0.04
-
glyoxylate
-
Klebsiella aerogenes
7.2.4.2 0.06
-
2-Oxomalonate
-
Klebsiella aerogenes
7.2.4.2 1.3
-
pyruvate product inhibition competitive for oxaloacetate Klebsiella aerogenes