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Literature summary extracted from

  • Kerjan, P.; Cerini, C.; Semeriva, M.; Mirande, M.
    The multienzyme complex containing nine aminoacyl-tRNA synthetases is ubiquitous from Drosophila to mammals (1994), Biochim. Biophys. Acta, 1199, 293-297.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.1.1.4 1200000
-
 gel filtration, multienzyme complex Drosophila sp. (in: flies)

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.4 Bacteria
-
-
-
6.1.1.4 Drosophila sp. (in: flies)
-
-
-
6.1.1.4 eukaryota
-
-
-
6.1.1.4 Mammalia
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.1.1.4
-
 Drosophila sp. (in: flies)

Storage Stability

EC Number Storage Stability Organism
6.1.1.4 -20°C Drosophila sp. (in: flies)

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.4 ATP + L-leucine + tRNALeu
-
 Mammalia AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
6.1.1.4 ATP + L-leucine + tRNALeu
-
 Bacteria AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
6.1.1.4 ATP + L-leucine + tRNALeu
-
 eukaryota AMP + diphosphate + L-leucyl-tRNALeu
-
 ?
6.1.1.4 ATP + L-leucine + tRNALeu
-
 Drosophila sp. (in: flies) AMP + diphosphate + L-leucyl-tRNALeu
-
 ?

Subunits

EC Number Subunits Comment Organism
6.1.1.4 ? prokaryotes and lower eukaryotes: the corresponding enzymes behave as free enzymes Bacteria
6.1.1.4 ? prokaryotes and lower eukaryotes: the corresponding enzymes behave as free enzymes eukaryota
6.1.1.4 ? the multienzyme complex is composed of 10 distinct polypeptides with MW ranging from 18000 to 165000 Drosophila sp. (in: flies)
6.1.1.4 ? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp Mammalia
6.1.1.4 ? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp eukaryota
6.1.1.4 ? in mammalia and higher eukaryotes: multienzyme complex containing 9 amino acyl-tRNA synthetases specific for Glu, Pro, Ile, Leu, Gln, Lys, Arg and Asp Drosophila sp. (in: flies)