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Literature summary extracted from

  • Blethen, S.L.; Boeker, E.A.; Snell, E.E.
    Arginine decarboxylase from Escherichia coli: Arginine decarboxylase from escherichia coli. I. Purification and specificity for substrates and coenzyme (1968), J. Biol. Chem., 243, 1671-1677.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.19 2-Norpyridoxal phosphate reactivation of the apoenzyme Escherichia coli
4.1.1.19 6-Methylpyridoxal phosphate reactivation of the apoenzyme Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.19 2-Nor-2-butylpyridoxal phosphate
-
Escherichia coli
4.1.1.19 5-Deoxypyridoxal
-
Escherichia coli
4.1.1.19 agmatine
-
Escherichia coli
4.1.1.19 beta-(2-Methyl-3-hydroxy-4-formylpyridine-5)-propionic acid
-
Escherichia coli
4.1.1.19 citrulline
-
Escherichia coli
4.1.1.19 guanidine
-
Escherichia coli
4.1.1.19 Guanidinoacetic acid
-
Escherichia coli
4.1.1.19 L-2-Amino-3-guanidinopropanoate
-
Escherichia coli
4.1.1.19 L-2-amino-5-guanidinopentanoate
-
Escherichia coli
4.1.1.19 L-2-amino-6-guanidinohexanoate
-
Escherichia coli
4.1.1.19 L-2-Chloro-5-guanidinopentanoate
-
Escherichia coli
4.1.1.19 L-2-Hydroxy-5-guanidinopentanoate
-
Escherichia coli
4.1.1.19 L-Lys
-
Escherichia coli
4.1.1.19 methylguanidine
-
Escherichia coli
4.1.1.19 Orn L-Orn Escherichia coli
4.1.1.19 pyridoxal
-
Escherichia coli
4.1.1.19 spermidine
-
Escherichia coli
4.1.1.19 Urea
-
Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.19 0.65
-
L-Arg
-
Escherichia coli
4.1.1.19 1.2
-
L-canavanine
-
Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.19 Escherichia coli
-
-
-
4.1.1.19 Escherichia coli B / ATCC 11303
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.19
-
Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.19 350 370
-
Escherichia coli
4.1.1.19 410
-
-
Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.19 L-arginine
-
Escherichia coli agmatine + CO2
-
?
4.1.1.19 L-arginine
-
Escherichia coli B / ATCC 11303 agmatine + CO2
-
?
4.1.1.19 L-Canavanine
-
Escherichia coli ?
-
?
4.1.1.19 L-Canavanine
-
Escherichia coli B / ATCC 11303 ?
-
?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.19 37 40
-
Escherichia coli

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.19 20 50 20°C: about 40% of maximal activity, 50°C: about 70% of maximal activity Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.19 5.2
-
-
Escherichia coli

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.19 3.5 7 pH 3.5: about 50% of maximal activity, pH 7.0: 23% of maximal activity Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.19 pyridoxal 5'-phosphate a formyl group of pyridoxal 5'-phosphate is bound to the 6-amino group of a Lys residue. Binds 10 mol of pyridoxal 5'-phosphate per mol of enzyme Escherichia coli