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Literature summary extracted from
- Studies on ornithine decarboxylase from the liver of thioacetamide-treated rats (1972), Biochim. Biophys. Acta, 284, 285-297.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.17 | 2-mercaptoethanol | - |
Rattus norvegicus |  |
| 4.1.1.17 | dithiothreitol | increases activity | Rattus norvegicus | |
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 4.1.1.17 | repeated freezing and thawing results in progressive inactivation | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.17 | D-Orn | weak | Rattus norvegicus | |
| 4.1.1.17 | histamine | - |
Rattus norvegicus | |
| 4.1.1.17 | Isonicotinic acid hydrazide | - |
Rattus norvegicus | |
| 4.1.1.17 | L-canaline | - |
Rattus norvegicus | |
| 4.1.1.17 | putrescine | - |
Rattus norvegicus | |
| 4.1.1.17 | spermidine | weak | Rattus norvegicus | |
| 4.1.1.17 | spermine | - |
Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.17 | 0.2 | - |
L-Orn | - |
Rattus norvegicus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.17 | 100000 | - |
gel filtration | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.17 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.17 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.17 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.17 | 0.193 | - |
- |
Rattus norvegicus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.1.1.17 | -20°C, 5 mM dithiothreitol, stable for at least 1 week | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.17 | L-Orn | - |
Rattus norvegicus | Putrescine + CO2 | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.17 | 7 | - |
- |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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