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Literature summary extracted from

  • Sklaviadis, T.K.; Georgatsos, J.G.; Kyriakidis, D.A.
    Purification and properties of ornithine decarboxylase from Tetrahymena pyriformis (1985), Biochim. Biophys. Acta, 831, 288-296.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 alpha-DL-difluoromethylornithine the nuclear enzyme is slightly more sensitive than the cytosolic Tetrahymena pyriformis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.17 0.0047
-
 L-Orn
-
 Tetrahymena pyriformis
4.1.1.17 0.5
-
 L-Lys
-
 Tetrahymena pyriformis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.17 cytosol
-
 Tetrahymena pyriformis 5829
-
4.1.1.17 nucleus
-
 Tetrahymena pyriformis 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.17 64000
-
 gel filtration Tetrahymena pyriformis

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Tetrahymena pyriformis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.17
-
 Tetrahymena pyriformis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.17 cell culture maximal activity in the middle and late log phases of growth Tetrahymena pyriformis
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.17 0.23
-
-
 Tetrahymena pyriformis

Storage Stability

EC Number Storage Stability Organism
4.1.1.17 -20°C, unstable in absence of pyridoxal 5'-phosphate Tetrahymena pyriformis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-Lys
-
 Tetrahymena pyriformis 1,5-diaminopentane + CO2
-
 ?
4.1.1.17 L-Orn
-
 Tetrahymena pyriformis Putrescine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.17 monomer 1 * 64000, SDS-PAGE Tetrahymena pyriformis