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Literature summary extracted from

  • Hiratsuka, A.; Yamane, H.; Yamazaki, S.; Ozawa, N.; Watabe, T.
    Subunit Ya-specific glutathione peroxidase activity toward cholesterol 7-hydroperoxides of glutathione S-transferases in cytosols from rat liver and skin (1997), J. Biol. Chem., 272, 4763-4769.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.11.1.9 0.003
-
 cholesterol 7beta-hydroperoxide
-
 Rattus norvegicus
1.11.1.9 0.004
-
 cholesterol 5alpha-hydroperoxide
-
 Rattus norvegicus
1.11.1.9 0.011
-
 cholesterol 7alpha-hydroperoxide
-
 Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.11.1.9 selenium selenocysteine Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.11.1.9 cumene hydroperoxide + GSH Rattus norvegicus
-
 ?
-
 ?
1.11.1.9 glutathione + ROOH Rattus norvegicus
-
 glutathione disulfide + ROH + H2O
-
 ?
1.11.1.9 H2O2 + GSH Rattus norvegicus
-
 H2O + GSSG
-
 ?
1.11.1.9 linolenic acid hydroperoxide + GSH Rattus norvegicus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.11.1.9
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.1.9 liver
-
 Rattus norvegicus
-
1.11.1.9 skin
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.11.1.9 0.07
-
 cholesterol 5alpha-hydroperoxide Rattus norvegicus
1.11.1.9 0.1
-
 cholesterol 7beta-hydroperoxide Rattus norvegicus
1.11.1.9 0.18
-
 cholesterol 7alpha-hydroperoxide Rattus norvegicus
1.11.1.9 402
-
 linolenic acid hydroperoxide Rattus norvegicus
1.11.1.9 408
-
 linoleic acid hydroperoxide Rattus norvegicus
1.11.1.9 445
-
 H2O2 Rattus norvegicus
1.11.1.9 472
-
 cumene hydroperoxide Rattus norvegicus
1.11.1.9 511
-
 arachidonic acid 15-hydroperoxide Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.9 arachidonic acid 15-hydroperoxide + GSH
-
 Rattus norvegicus 15-hydroxyarachidonic acid + GSSG
-
 ?
1.11.1.9 cholesterol 5alpha-hydroperoxide + GSH
-
 Rattus norvegicus 5alpha-hydroxycholesterol + GSSG
-
 ?
1.11.1.9 cholesterol 7alpha-hydroperoxide + GSH
-
 Rattus norvegicus 7alpha-hydroxycholesterol + GSSG
-
 ?
1.11.1.9 cholesterol 7beta-hydroperoxide + GSH
-
 Rattus norvegicus 7beta-hydroxycholesterol + GSSG
-
 ?
1.11.1.9 cumene hydroperoxide + GSH
-
 Rattus norvegicus ?
-
 ?
1.11.1.9 glutathione + ROOH
-
 Rattus norvegicus glutathione disulfide + ROH + H2O
-
 ?
1.11.1.9 H2O2 + GSH
-
 Rattus norvegicus H2O + GSSG
-
 ?
1.11.1.9 linoleic acid hydroperoxide + GSH
-
 Rattus norvegicus ?
-
 ?
1.11.1.9 linolenic acid hydroperoxide + GSH
-
 Rattus norvegicus ?
-
 ?