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Literature summary extracted from
- Glutathione peroxidase (1981), Methods Enzymol., 77, 325-333.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.11.1.9 | - |
Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.11.1.9 | Ag+ | - |
Bos taurus |  |
| 1.11.1.9 | Chloroacetate | - |
Bos taurus | |
| 1.11.1.9 | iodoacetate | - |
Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.9 | 21900 | - |
alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE | Bos taurus |
| 1.11.1.9 | 75000 | 85500 | gel filtration | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.9 | glutathione + ROOH | Mammalia | cumene hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | cumene hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Mammalia | ethyl hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | ethyl hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | cholesterol 7beta-hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Mammalia | peroxidized DNA | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | peroxidized DNA | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | pregnenolone 17alpha-hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Mammalia | thymine hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | thymine hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Mammalia | highly specific for glutathione | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | highly specific for glutathione | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Mammalia | linoleic acid hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | Bos taurus | linoleic acid hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.11.1.9 | Bos taurus | - |
- |
- |
| 1.11.1.9 | Mammalia | - |
- |
- |
| 1.11.1.9 | no activity in plants | - |
- |
- |
Oxidation Stability
| EC Number | Oxidation Stability | Organism |
|---|---|---|
| 1.11.1.9 | autooxidation, reactivation by glutathione | Mammalia |
| 1.11.1.9 | autooxidation, reactivation by glutathione | Bos taurus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.11.1.9 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.11.1.9 | blood | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.11.1.9 | glutathione + ROOH | cumene hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | cumene hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | ethyl hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | ethyl hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | cholesterol 7beta-hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | peroxidized DNA | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | peroxidized DNA | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | pregnenolone 17alpha-hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | thymine hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | thymine hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | highly specific for glutathione | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | highly specific for glutathione | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | linoleic acid hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
| 1.11.1.9 | glutathione + ROOH | linoleic acid hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.11.1.9 | homotetramer | - |
Mammalia |
| 1.11.1.9 | homotetramer | alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE | Bos taurus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.9 | 42 | - |
- |
Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.9 | 8.8 | - |
- |
Bos taurus |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.11.1.9 | 7 | 10 | - |
Bos taurus |
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Release 2023.1 (January 2023)
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