Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fujioka, M.
    Active-site residues of saccharopine dehydrogenase (NAD+, lysine-forming) from bakers yeast (1981), Biochem. Soc. Trans., 9, 281-282.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.7 diethyldicarbonate
-
 Saccharomyces cerevisiae
1.5.1.7 pyridoxal 5'-phosphate reversible inactivation Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.7 N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O Saccharomyces cerevisiae last step of alpha-aminoadipate pathway for lysine biosynthesis L-lysine + 2-oxoglutarate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.7 Saccharomyces cerevisiae
-
 baker's yeast
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.5.1.7 N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+ mechanism Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.7 N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O last step of alpha-aminoadipate pathway for lysine biosynthesis Saccharomyces cerevisiae L-lysine + 2-oxoglutarate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.7 NAD+
-
 Saccharomyces cerevisiae