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Literature summary extracted from
- Identification of mammalian aspartate-4-decarboxylase (1985), Arch. Biochem. Biophys., 238, 435-446.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.12 | hydroxylamine | - |
Rattus norvegicus |  |
| 4.1.1.12 | potassium borohydride | - |
Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.12 | 0.095 | - |
L-Asp | - |
Rattus norvegicus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.12 | Bos taurus | - |
- |
- |
| 4.1.1.12 | Felis catus | - |
- |
- |
| 4.1.1.12 | Gallus gallus | - |
- |
- |
| 4.1.1.12 | Mus musculus | - |
- |
- |
| 4.1.1.12 | Rattus norvegicus | - |
- |
- |
| 4.1.1.12 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.12 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.12 | heart | - |
Rattus norvegicus | - |
| 4.1.1.12 | kidney | - |
Rattus norvegicus | - |
| 4.1.1.12 | liver | - |
Gallus gallus | - |
| 4.1.1.12 | liver | - |
Mus musculus | - |
| 4.1.1.12 | liver | - |
Rattus norvegicus | - |
| 4.1.1.12 | liver | - |
Sus scrofa | - |
| 4.1.1.12 | liver | - |
Bos taurus | - |
| 4.1.1.12 | liver | - |
Felis catus | - |
| 4.1.1.12 | pancreas | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.12 | additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.12 | L-Asp | - |
Gallus gallus | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Asp | - |
Mus musculus | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Asp | - |
Rattus norvegicus | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Asp | - |
Sus scrofa | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Asp | - |
Bos taurus | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Asp | - |
Felis catus | L-Ala + CO2 | - |
? | |
| 4.1.1.12 | L-Cysteinesulfinate | - |
Rattus norvegicus | L-Ala + SO2 | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Gallus gallus | ? | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Mus musculus | ? | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Rattus norvegicus | ? | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Sus scrofa | ? | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Bos taurus | ? | - |
? | |
| 4.1.1.12 | additional information | no inherent transaminase activity | Felis catus | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.12 | 7 | - |
- |
Rattus norvegicus |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.12 | 6 | - |
irreversible inactivation below | Rattus norvegicus |
| 4.1.1.12 | 10 | - |
stable up to | Rattus norvegicus |
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Release 2023.1 (January 2023)
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