Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Watkins, W.J.; Goldring, C.E.P.; Gower, D.B.
    Properties of 4-ene-5alpha-reductase in porcine testicular microsomes (1986), Biochem. Soc. Trans., 14, 339-340.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.1.22 0.0006
-
 testosterone
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.1.22 microsome
-
 Sus scrofa
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.22 testosterone + NADPH + H+ Sus scrofa
-
 17beta-hydroxy-5alpha-androstan-3-one + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.22 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.22 testis
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.22 cholest-4-en-3-one + NADPH
-
 Sus scrofa 5-alpha-cholestan-3-one + NADP+
-
 ?
1.3.1.22 testosterone + NADPH + H+
-
 Sus scrofa 17beta-hydroxy-5alpha-androstan-3-one + NADP+
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.3.1.22 32
-
-
 Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.22 6.9
-
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.22 additional information absolute requirement for NADPH in rat epididymis Sus scrofa
1.3.1.22 additional information NADH: low avtivity Sus scrofa
1.3.1.22 NADPH absolute requirement for NADPH Sus scrofa