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Literature summary extracted from

  • Wikström, M.; Krab, K.; Saraste, M.
    Proton-translocating cytochrome complexes (1981), Annu. Rev. Biochem., 50, 623-655.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
7.1.1.8
-
 Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.8 Antimycin
-
 Bos taurus
7.1.1.8 Antimycin
-
 Paracoccus denitrificans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.8 membrane
-
 Paracoccus denitrificans 16020
-
7.1.1.8 membrane
-
 Bos taurus 16020
-
7.1.1.8 membrane
-
 Neurospora crassa 16020
-
7.1.1.8 mitochondrion
-
 Bos taurus 5739
-
7.1.1.8 mitochondrion
-
 Neurospora crassa 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.1.1.9 Cu
-
 Bacteria
7.1.1.9 Cu
-
 eukaryota
7.1.1.9 Cu
-
 Bos taurus
7.1.1.9 Cu
-
 Neurospora crassa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.1.1.8 6000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 8000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 9000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 12000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 12000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 14000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 24000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 25000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 28000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 29000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 30000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 31000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 43000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 45000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 46000
-
 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 52000
-
 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.8 240000 250000 from concentration of prosthetic groups Bos taurus
7.1.1.8 250000
-
 from subunit composition Bos taurus
7.1.1.8 285000
-
-
 Bos taurus
7.1.1.8 285000
-
 from concentration of prosthetic groups Neurospora crassa
7.1.1.8 290000
-
 from subunit composition Neurospora crassa
7.1.1.8 440000
-
 from hydrodynamic measurements Bos taurus
7.1.1.8 550000
-
 from hydrodynamic measurements Neurospora crassa
7.1.1.9 9000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 12000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 14000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 18000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 21000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 29000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa
7.1.1.9 40000
-
 I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.8 Bos taurus
-
-
-
7.1.1.8 Neurospora crassa
-
-
-
7.1.1.8 Paracoccus denitrificans
-
-
-
7.1.1.9 Bacteria
-
-
-
7.1.1.9 Bos taurus
-
-
-
7.1.1.9 eukaryota
-
-
-
7.1.1.9 Neurospora crassa
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
7.1.1.9 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O mechanism of proton pumping Bacteria
a
7.1.1.9 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O mechanism of proton pumping eukaryota
a
7.1.1.9 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O mechanism of proton pumping Bos taurus
a
7.1.1.9 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O mechanism of proton pumping Neurospora crassa
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.1.1.8 heart
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Paracoccus denitrificans ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Bos taurus ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Neurospora crassa ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?

Subunits

EC Number Subunits Comment Organism
7.1.1.8 dimer
-
 Bos taurus
7.1.1.8 dimer
-
 Neurospora crassa
7.1.1.8 octamer 1 * 46000 + 1 * 43000 + 1 * 29000 + 1 * 28000 + 1 * 24000 + 1 * 12000 + 1 * 8000 + 1 * 6000, SDS-PAGE Bos taurus
7.1.1.8 octamer 1 * 52000 + 1 * 45000 + 1 * 31000 + 1 * 30000 + 1 * 25000 + 1 * 14000 + 1 * 12000 + 1 * 9000, SDS-PAGE Neurospora crassa
7.1.1.9 oligomer
-
 Bacteria
7.1.1.9 oligomer
-
 eukaryota
7.1.1.9 oligomer
-
 Bos taurus
7.1.1.9 oligomer I, II, III, IV, V, VI, VII, 1 * 40000 + 1 * 29000 + 1 * 21000 + 1 * 18000 + 1 * 14000 + 1 * 12000 + 1 * 9000, proposed subunit composition, stoichiometry Neurospora crassa

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.9 heme a
-
 Bacteria
7.1.1.9 heme a
-
 eukaryota
7.1.1.9 heme a
-
 Bos taurus
7.1.1.9 heme a
-
 Neurospora crassa
7.1.1.9 Heme a3
-
 Bacteria
7.1.1.9 Heme a3
-
 Bos taurus
7.1.1.9 Heme a3
-
 Neurospora crassa
7.1.1.9 Heme a3 closely associated with CuB eukaryota