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Literature summary extracted from

  • Chin, N.W.; Trela, J.M.
    Comparison of acetohydroxy-acid synthetases from two extreme thermophilic bacteria (1973), J. Bacteriol., 114, 674-678.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.6 Ile
-
 Bacillus sp. (in: Bacteria)
2.2.1.6 Ile
-
 Thermus aquaticus
2.2.1.6 Leu no inhibition Bacillus sp. (in: Bacteria)
2.2.1.6 Leu no inhibition Thermus aquaticus
2.2.1.6 Val competitive; feed-back inhibition Bacillus sp. (in: Bacteria)
2.2.1.6 Val feed-back inhibition; noncompetitive Thermus aquaticus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.2.1.6 Mg2+ required Thermus aquaticus
2.2.1.6 Mg2+ required Bacillus sp. (in: Bacteria)

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.6 Bacillus sp. (in: Bacteria)
-
-
-
2.2.1.6 Thermus aquaticus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.6 pyruvate
-
 Thermus aquaticus 2-acetolactate + CO2
-
 ?
2.2.1.6 pyruvate
-
 Bacillus sp. (in: Bacteria) 2-acetolactate + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.2.1.6 70
-
-
 Thermus aquaticus
2.2.1.6 75
-
-
 Bacillus sp. (in: Bacteria)

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.2.1.6 additional information
-
-
 Thermus aquaticus
2.2.1.6 additional information
-
-
 Bacillus sp. (in: Bacteria)

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.2.1.6 6
-
-
 Bacillus sp. (in: Bacteria)
2.2.1.6 8
-
-
 Thermus aquaticus

Cofactor

EC Number Cofactor Comment Organism Structure
2.2.1.6 FAD required Thermus aquaticus
2.2.1.6 FAD no requirement Bacillus sp. (in: Bacteria)
2.2.1.6 thiamine diphosphate required as cofactor Thermus aquaticus
2.2.1.6 thiamine diphosphate required as cofactor Bacillus sp. (in: Bacteria)