EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | 2-mercaptoethanol | stimulates | Euglena gracilis | |
2.2.1.6 | dithiothreitol | stimulates | Euglena gracilis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | 2-oxobutanoate | inhibits formation of acetolactate from pyruvate | Euglena gracilis | |
2.2.1.6 | Ile | 5 mM, 32% inhibition | Euglena gracilis | |
2.2.1.6 | L-2-aminobutanoate | 5 mM, 21% inhibition | Euglena gracilis | |
2.2.1.6 | L-Thr | 5 mM, 6.6% inhibition | Euglena gracilis | |
2.2.1.6 | Leu | 5 mM, 23% inhibition | Euglena gracilis | |
2.2.1.6 | Val | 5 mM, 89% inhibition; feed-back inhibition; noncompetitive | Euglena gracilis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.2.1.6 | 2.1 | - |
pyruvate | - |
Euglena gracilis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.2.1.6 | mitochondrion | - |
Euglena gracilis | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.2.1.6 | pyruvate | Euglena gracilis | key enzyme in synthesis of branched-chain amino acids | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.2.1.6 | Euglena gracilis | - |
- |
- |
EC Number | Storage Stability | Organism |
---|---|---|
2.2.1.6 | 4°C, 24 h, 36% loss of activity | Euglena gracilis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.2.1.6 | pyruvate | - |
Euglena gracilis | 2-acetolactate + CO2 | - |
? | |
2.2.1.6 | pyruvate | key enzyme in synthesis of branched-chain amino acids | Euglena gracilis | ? | - |
? | |
2.2.1.6 | pyruvate + 2-oxobutanoate | much higher affinity for 2-oxobutanoate than for pyruvate | Euglena gracilis | acetohydroxybutanoate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.2.1.6 | 50 | - |
- |
Euglena gracilis |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.2.1.6 | 7.5 | - |
- |
Euglena gracilis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.2.1.6 | ATP | activates | Euglena gracilis |