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Literature summary extracted from
- The nature of the enzymatic reduction of the mixed disulfide of coenzyme A and glutathione (1974), FEBS Lett., 39, 296-300.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.8.1.10 | cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.10 | CoA-glutathione + NADPH | Rattus norvegicus | - |
glutathione + CoA + NADP+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.10 | Rattus norvegicus | - |
male sprague-dawley rats | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.8.1.10 | not separated from GSSG reductase activity, EC 1.6.4.2 | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.1.10 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.10 | CoA-glutathione + NADPH | - |
Rattus norvegicus | glutathione + CoA + NADP+ | - |
? | |
| 1.8.1.10 | CoA-glutathione + NADPH | - |
Rattus norvegicus | glutathione + CoA + NADP+ | - |
ir | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.10 | NADPH | NADPH-dependent | Rattus norvegicus | |
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Release 2023.1 (January 2023)
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