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Literature summary extracted from
- Rat liver levels of coenzyme A-glutathione and of enzymes in its metabolism (1972), Arch. Biochem. Biophys., 153, 619-626.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.10 | CoA-glutathione + NADPH | Rattus norvegicus | may be important in metabolism of CoASSG | glutathione + CoA + NADP+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.10 | Rattus norvegicus | - |
male albino, normal and alloxan diabetic rats, no change of enzyme activity and CoASSG content in diabetic rats | - |
| 1.8.4.3 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.1.10 | liver | - |
Rattus norvegicus | - |
| 1.8.4.3 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.10 | 0.0007 | - |
alloxan diabetic rats, liver extract | Rattus norvegicus |
| 1.8.1.10 | 0.00085 | - |
normal rats, liver extract | Rattus norvegicus |
| 1.8.4.3 | 12000 | - |
transhydrogenase of normal rat | Rattus norvegicus |
| 1.8.4.3 | 13300 | - |
transhydrogenase of diabetic rat | Rattus norvegicus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.8.1.10 | 4°C, dialyzed extract, 16 hours, stable | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.10 | CoA-glutathione + NADPH | - |
Rattus norvegicus | glutathione + CoA + NADP+ | - |
? | |
| 1.8.1.10 | CoA-glutathione + NADPH | may be important in metabolism of CoASSG | Rattus norvegicus | glutathione + CoA + NADP+ | - |
? | |
| 1.8.4.3 | CoA-glutathione + GSH | - |
Rattus norvegicus | CoA + GSSG | - |
r | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.10 | 25 | - |
assay at | Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.10 | NADPH | NADPH-dependent | Rattus norvegicus | |
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Release 2023.1 (January 2023)
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