Literature summary extracted from

De Rudder, K.E.E.; Sohlenkamp, C.; Geiger, O.
Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase (1999), J. Biol. Chem., 274, 20011-20016.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.8.24	Triton X-100	optimal activation at 0.2%, w/v	Sinorhizobium meliloti

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.8.24	Triton X-100	inhibitory at higher concentrations	Sinorhizobium meliloti

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.7.8.24	Mg2+	20fold less effective than Mn2+	Sinorhizobium meliloti
2.7.8.24	Mn2+	optimal activation at 10 mM, more effective than Mg2+	Sinorhizobium meliloti

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.8.24	CDP-diacylglycerol + choline	Sinorhizobium meliloti	second bacterial pathway for phosphatidylcholine biosynthesis	CMP + phosphatidylcholine	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.8.24	Sinorhizobium meliloti	-	Rhizobium	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.8.24	cell culture	-	Sinorhizobium meliloti	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.8.24	CDP-diacylglycerol + choline	second bacterial pathway for phosphatidylcholine biosynthesis	Sinorhizobium meliloti	CMP + phosphatidylcholine	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.7.8.24	8	-	-	Sinorhizobium meliloti

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Release 2023.1 (January 2023)