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Literature summary extracted from

  • Larsson, A.
    Thioredoxin reductase from rat liver (1973), Eur. J. Biochem., 35, 346-349.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.1.9 additional information Rattus norvegicus ribonucleotide reductase, thioredoxin and thioredoxin reductase constitute a system necessary for the biosynthesis of deesoxyribonucleotides ?
-
 ?
1.8.1.9 thioredoxin + NADP+ Rattus norvegicus
-
 thioredoxin disulfide + NADPH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.1.9
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.9 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.8.1.9 additional information
-
-
 Rattus norvegicus
1.8.1.9 0.595
-
 purified enzyme Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
1.8.1.9 -20°C, several months Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.9 additional information specific for NADPH, B side of nicotinamide ring Rattus norvegicus ?
-
 ?
1.8.1.9 additional information ribonucleotide reductase, thioredoxin and thioredoxin reductase constitute a system necessary for the biosynthesis of deesoxyribonucleotides Rattus norvegicus ?
-
 ?
1.8.1.9 thioredoxin + NADP+
-
 Rattus norvegicus thioredoxin disulfide + NADPH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.9 FAD
-
 Rattus norvegicus
1.8.1.9 NADPH specific for Rattus norvegicus