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Literature summary extracted from

  • Holmgren, A.; Lyckeborg, C.
    Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase (1980), Proc. Natl. Acad. Sci. USA, 77, 5149-5152.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.1.9 0.07
-
 thioredoxin
-
 Bos taurus
1.8.1.9 0.33
-
 thioredoxin
-
 Bos taurus
1.8.1.9 0.33
-
 alloxan
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.1.9 110000
-
 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.9 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.1.9
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.9 thymus
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.9 alloxan + NADPH
-
 Bos taurus ?
-
 ?
1.8.1.9 thioredoxin + NADP+
-
 Bos taurus thioredoxin disulfide + NADPH
-
 ir
1.8.1.9 thioredoxin + NADP+
-
 Bos taurus thioredoxin disulfide + NADPH + H+
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.8.1.9 25
-
 assay at Bos taurus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.8.1.9 167
-
 alloxan
-
 Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.8.1.9 7
-
 assay at Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.9 NADPH
-
 Bos taurus