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Literature summary extracted from

  • Kohnert, K.D.; Hahn, H.J.; Zuhlke, H.; Schmidt, S.; Fiedler, H.
    Breakdown of exogenous insulin by Langerhans islets of the pancreas in vitro (1974), Biochim. Biophys. Acta, 338, 68-77.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.4.2 0.014
-
 Insulin
-
 Rattus norvegicus
1.8.4.2 1.28
-
 GSH
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.8.4.2 Mus musculus
-
-
-
1.8.4.2 Rattus norvegicus
-
 Wistar rat
-
1.8.4.2 Rattus norvegicus
-
 sand rat, i.e. Psammomys obesus
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.4.2 pancreas pancreatic islets Mus musculus
-
1.8.4.2 pancreas pancreatic islets Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.8.4.2 9.81
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.4.2 GSH + protein disulfide
-
 Mus musculus GSSG + protein-dithiol
-
 ?
1.8.4.2 GSH + protein disulfide
-
 Rattus norvegicus GSSG + protein-dithiol
-
 ?
1.8.4.2 thioglycolic acid + protein disulfide
-
 Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.8.4.2 7.2
-
-
 Rattus norvegicus