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Literature summary extracted from
- Insulin degradation. X. Identification of insulin degrading activity of rat liver plasma membrane as glutathione-insulin transhydrogenase (1973), Biochem. Biophys. Res. Commun., 55, 689-696.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.8.4.2 | membrane | plasma membrane | Rattus norvegicus | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.4.2 | GSH + protein disulfide | Rattus norvegicus | initial step in sequential insulin degradation | GSSG + protein-dithiol | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.4.2 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.4.2 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.4.2 | GSH + protein disulfide | - |
Rattus norvegicus | GSSG + protein-dithiol | - |
? | |
| 1.8.4.2 | GSH + protein disulfide | initial step in sequential insulin degradation | Rattus norvegicus | GSSG + protein-dithiol | - |
? | |
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Release 2023.1 (January 2023)
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