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Literature summary extracted from
- Characterization of glutathione reductase from porcine erythrocytes (1978), Biochim. Biophys. Acta, 527, 337-347.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.8.1.7 | additional information | - |
additional information | - |
Sus scrofa |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.7 | 59000 | - |
2 * 59000, SDS-PAGE | Sus scrofa |
| 1.8.1.7 | 103000 | - |
analytical ultracentrifugation | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.7 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.8.1.7 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.1.7 | erythrocyte | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.7 | GSSG + NADPH | S-sulfoglutathione and some mixed disulfides, with the exception of the mixed disulfide of coenzyme A and GSH, are poor substrates | Sus scrofa | glutathione + NADP+ | - |
? |  |
| 1.8.1.7 | additional information | low transhydrogenase activity with oxidized pyridine nucleotide analogs and diaphorase activity with 2,6-dichlorophenolindophenol as acceptor substrates, NADPH and NADH as donors | Sus scrofa | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.8.1.7 | dimer | 2 * 59000, SDS-PAGE | Sus scrofa |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.7 | 30 | - |
assay at | Sus scrofa |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.7 | 5 | - |
NADH + GSSG | Sus scrofa |
| 1.8.1.7 | 7 | - |
NADPH + GSSG | Sus scrofa |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.7 | FAD | 2 mol of FAD per mol of enzyme | Sus scrofa | |
| 1.8.1.7 | FAD | FAD enzyme | Sus scrofa | |
| 1.8.1.7 | NADH | 200times less effective than NADPH | Sus scrofa | |
| 1.8.1.7 | NADPH | 200times more activity than with NADH | Sus scrofa | |
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Release 2023.1 (January 2023)
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