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Literature summary extracted from

  • Sumizu, K.
    Oxidation of hypotaurine in rat liver (1962), Biochim. Biophys. Acta, 63, 210 - 212.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.13.8 2-mercaptoethanolamine 1 mM Rattus norvegicus
1.14.13.8 cysteine 1 mM Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.8 ammonium sulfate 10 mM Rattus norvegicus
1.14.13.8 KCN 0.1 mM Rattus norvegicus
1.14.13.8 phosphate 10 mM Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.8 hypotaurine + H2O + NAD+ Rattus norvegicus metabolism of cysteine taurine + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.8 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.13.8 ammonium sulfate precipitation, dialysis Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.8 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
1.14.13.8 frozen., 0.1 M Tris-HCl, pH 7.4, 36 h 50% loss of activity, loses total activity within 4 days Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.8 hypotaurine + H2O + NAD+
-
 Rattus norvegicus taurine + NADH
-
 ?
1.14.13.8 hypotaurine + H2O + NAD+ metabolism of cysteine Rattus norvegicus taurine + NADH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.13.8 7.5 7.8
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.8 NAD+
-
 Rattus norvegicus
1.14.13.8 NADP+ slightly effective Rattus norvegicus