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Literature summary extracted from

  • McCauley, R.
    Properties of a monoamine oxidase from rat liver mitochondrial outer membranes (1978), Arch. Biochem. Biophys., 189, 8-13.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 Clorgyline MAO-A highly sensitive and MAO-B less sensitive to inhibition; poor inhibition Rattus norvegicus
1.4.3.4 Deprenyl MAO-B sensitive Rattus norvegicus
1.4.3.4 Pargyline MAO-B sensitive Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.4 additional information
-
additional information Km of mitochondrial outer membrane and purified enzyme Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrial outer membrane
-
Rattus norvegicus 5741
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.4 65000
-
x * 65000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.4
-
Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 liver
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.4 0.8
-
-
Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 2-phenylethylamine + H2O + O2
-
Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
?
1.4.3.4 benzylamine + H2O + O2
-
Rattus norvegicus benzaldehyde + NH3 + H2O2
-
?
1.4.3.4 dopamine + H2O + O2
-
Rattus norvegicus (3,4-dihydroxyphenyl)acetaldehyde + NH3 + H2O2
-
?
1.4.3.4 RCH2NH2 + H2O + O2 norepinephrine Rattus norvegicus RCHO + NH3 + H2O2
-
?
1.4.3.4 RCH2NH2 + H2O + O2 octopamine Rattus norvegicus RCHO + NH3 + H2O2
-
?
1.4.3.4 serotonin + H2O + O2
-
Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
1.4.3.4 tyramine + H2O + O2
-
Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
?

Subunits

EC Number Subunits Comment Organism
1.4.3.4 ? x * 65000, SDS-PAGE Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.4 flavin
-
Rattus norvegicus