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Literature summary extracted from

  • Hooper, A.B.; Terry, K.R.
    Hydroxylamine oxidoreductase of Nitrosomonas. Production of nitric oxide from hydroxylamine (1979), Biochim. Biophys. Acta, 571, 12-20.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.2.6 Ce(NH4)2(NO3)6 0.1 mM, stimulates the rate of oxidation of NH2OH 2.6-fold and inhibits production of HNO2 by 40% Nitrosomonas europaea
1.7.2.6 Co(NO3)2 0.1 mM, 70% inhibition of the rate of nitrite synthesis Nitrosomonas europaea
1.7.2.6 H2O2 inhibits one step of oxidation of NH2OH to HNO Nitrosomonas europaea
1.7.2.6 Mn2+ complete inhibition of nitrite synthesis at 0.1 mM; complete inhibition of the oxidation of HNO to NO at 0.001 mM, inhibition of HNO2 synthesis is the same at pH 6,7,8 and 9 Nitrosomonas europaea

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.7.2.6 Ce(NH4)2(NO3)6 0.1 mM, stimulates the rate of oxidation of NH2OH 2.6-fold and inhibits production of HNO2 by 40% Nitrosomonas europaea
1.7.2.6 Mn2+ 0.001 mM, stimulation of NH2OH utilization, stimulation at pH 6 and pH 9 is approximately 40% greater than at pH 7 and pH 8 Nitrosomonas europaea
1.7.2.6 additional information the presence of Mn2+ results in decreased formation of NO and increased formation of N2O Nitrosomonas europaea

Organism

EC Number Organism UniProt Comment Textmining
1.7.2.6 Nitrosomonas europaea
-
-
-
1.7.2.6 Nitrosomonas europaea Schmidt
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.7.2.6 ammonium sulfate precipitation, DEAE cellulose column chromatography, gel filtration Nitrosomonas europaea

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.2.6 hydroxylamine + ferricytochrome c + H2O
-
 Nitrosomonas europaea nitrite + ferrocytochrome c + H+
-
 ?
1.7.2.6 hydroxylamine + ferricytochrome c + H2O
-
 Nitrosomonas europaea Schmidt nitrite + ferrocytochrome c + H+
-
 ?
1.7.2.6 additional information oxidation of hydroxylamine by the enzyme results in the production of a mixture of HNO2/HNO3 Nitrosomonas europaea ?
-
 ?
1.7.2.6 additional information oxidation of hydroxylamine by the enzyme results in the production of a mixture of HNO2/HNO3 Nitrosomonas europaea Schmidt ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.7.2.6 hydroxylamine oxidoreductase
-
 Nitrosomonas europaea
1.7.2.6 hydroxylamine:oxygen oxidoreductase
-
 Nitrosomonas europaea