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Literature summary extracted from

  • Renart, M.F.; Sillero, A.
    GMP reductase in Artemia salina (1974), Biochim. Biophys. Acta, 341, 178-186.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.7.1.7 2-mercaptoethanol in absence of mercaptoethanol 50% of maximal velocity Artemia salina

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.1.7 IMP 1 mM, 10% inhibition, 2 mM, 20% inhibition Artemia salina
1.7.1.7 additional information not inhibited by ATP Artemia salina
1.7.1.7 p-hydroxymercuribenzoate
-
 Artemia salina

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.7.1.7 0.01
-
 GMP
-
 Artemia salina

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.7.1.7 250000
-
 gel filtration Artemia salina

Organism

EC Number Organism UniProt Comment Textmining
1.7.1.7 Artemia salina
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.7.1.7 partial Artemia salina

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.7.1.7 0.078
-
-
 Artemia salina

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.1.7 NADPH + guanosine 5'-phosphate the rate of the reverse reaction is 6% of the forward reaction Artemia salina NADP+ + inosine 5'-phosphate + NH3
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.7.1.7 8.5
-
-
 Artemia salina

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.7.1.7 7 9.5 pH 7: about 25% of activity at maximum, pH 9.5: about 30% of activity at maximum Artemia salina

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.1.7 NADP+
-
 Artemia salina
1.7.1.7 NADPH specific for Artemia salina

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.7.1.7 0.035
-
 IMP
-
 Artemia salina