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Literature summary extracted from

  • Steenkamp, D.J.; Beinert, H.
    Mechanistic studies on the dehydrogenases of methylotrophic bacteria. 1. The influence of substrate binding to reduced trimethylamine dehydrogenase on the intramolecular electron transfer between its prosthetic groups (1982), Biochem. J., 207, 233-239.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.8.2 Tetramethylammonium chloride noncompetitive inhibition Methylophilus methylotrophus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.5.8.2 Fe 4Fe-4S-center Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus physiological electron acceptor, biphasic reaction kinetic dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1 physiological electron acceptor, biphasic reaction kinetic dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.5.8.2 Methylophilus methylotrophus
-
-
-
1.5.8.2 Methylophilus methylotrophus W3A1
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.8.2
-
Methylophilus methylotrophus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.8.2 cell culture
-
Methylophilus methylotrophus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein physiological electron acceptor, biphasic reaction kinetic Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein physiological electron acceptor, biphasic reaction kinetic Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.8.2 8.5
-
-
Methylophilus methylotrophus

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.8.2 electron transferring flavoprotein
-
Methylophilus methylotrophus
1.5.8.2 FMN
-
Methylophilus methylotrophus