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Literature summary extracted from
- Studies of crystalline trimethyllamine dehydrogenase in three oxidation states and in the presence of substrate and inhibitor (1989), J. Biol. Chem., 264, 11887-11892.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.5.8.2 | macro-seeding of sitting drops, 6 A resolution | Methylophilus methylotrophus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.2 | Tetramethylammonium chloride | - |
Methylophilus methylotrophus |  |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.2 | Fe | 4Fe-4S-center | Methylophilus methylotrophus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.8.2 | trimethylamine + H2O + electron transferring flavoprotein | Methylophilus methylotrophus | - |
dimethylamine + formaldehyde + reduced electron transferring flavoprotein | - |
? | |
| 1.5.8.2 | trimethylamine + H2O + electron transferring flavoprotein | Methylophilus methylotrophus W3A1 | - |
dimethylamine + formaldehyde + reduced electron transferring flavoprotein | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.8.2 | Methylophilus methylotrophus | - |
- |
- |
| 1.5.8.2 | Methylophilus methylotrophus W3A1 | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.5.8.2 | cell culture | - |
Methylophilus methylotrophus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.8.2 | trimethylamine + H2O + electron transferring flavoprotein | - |
Methylophilus methylotrophus | dimethylamine + formaldehyde + reduced electron transferring flavoprotein | - |
? | |
| 1.5.8.2 | trimethylamine + H2O + electron transferring flavoprotein | - |
Methylophilus methylotrophus W3A1 | dimethylamine + formaldehyde + reduced electron transferring flavoprotein | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.8.2 | FMN | - |
Methylophilus methylotrophus | |
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Release 2023.1 (January 2023)
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