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Literature summary extracted from

  • Jones, M.; Talfournier, F.; Bobrov, A.; Grossmann, G.J.; Vekshin, N.; Sutcliffe, M.J.; Scrutton, N.S.
    Electron transfer and conformational change in complexes of trimethylamine dehydrogenase and electron transferring flavoprotein (2002), J. Biol. Chem., 277, 8457-8465.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
1.5.8.2 Y442F
-
 Methylophilus methylotrophus
1.5.8.2 Y442G
-
 Methylophilus methylotrophus
1.5.8.2 Y442L
-
 Methylophilus methylotrophus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.5.8.2 Fe
-
 Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus a series of conformational changes occur during assembly of the enzyme-electron transferring flavoprotein complex and electron transfer dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1 a series of conformational changes occur during assembly of the enzyme-electron transferring flavoprotein complex and electron transfer dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.8.2 Methylophilus methylotrophus
-
-
-
1.5.8.2 Methylophilus methylotrophus W3A1
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.8.2 to homogeneity, recombinant enzyme Methylophilus methylotrophus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.8.2 cell culture
-
 Methylophilus methylotrophus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein a series of conformational changes occur during assembly of the enzyme-electron transferring flavoprotein complex and electron transfer Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
1.5.8.2 trimethylamine + H2O + electron transferring flavoprotein a series of conformational changes occur during assembly of the enzyme-electron transferring flavoprotein complex and electron transfer Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.8.2 FMN
-
 Methylophilus methylotrophus