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Literature summary extracted from

  • Grisolia, S.; Reglero.A.; Rivas, J.
    N-Formyl-methionine deformylase of animal tissues (1977), Biochem. Biophys. Res. Commun., 77, 237-244.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.31 3.3
-
 N-formyl-methionine enzyme from spleen Rattus norvegicus
3.5.1.31 5
-
 N-formyl-methionine enzyme from brain, heart or muscle Rattus norvegicus
3.5.1.31 6.5
-
 N-formyl-methionine enzyme from kidney Rattus norvegicus
3.5.1.31 12.5
-
 N-formyl-methionine enzyme from liver Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.31 Bos taurus
-
-
-
3.5.1.31 Gallus gallus
-
-
-
3.5.1.31 Rattus norvegicus
-
-
-
3.5.1.31 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.31 brain
-
 Rattus norvegicus
-
3.5.1.31 brain
-
 Bos taurus
-
3.5.1.31 heart
-
 Rattus norvegicus
-
3.5.1.31 kidney
-
 Rattus norvegicus
-
3.5.1.31 kidney
-
 Sus scrofa
-
3.5.1.31 liver
-
 Gallus gallus
-
3.5.1.31 liver
-
 Rattus norvegicus
-
3.5.1.31 muscle
-
 Rattus norvegicus
-
3.5.1.31 spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.31 N-formyl-alanine + H2O at 2-7% of the activity with N-formyl-methionine, depending on tissue Rattus norvegicus formate + alanine
-
 ?
3.5.1.31 N-formyl-L-methionine + H2O
-
 Gallus gallus formate + L-methionine
-
 ?
3.5.1.31 N-formyl-L-methionine + H2O
-
 Rattus norvegicus formate + L-methionine
-
 ?
3.5.1.31 N-formyl-L-methionine + H2O
-
 Sus scrofa formate + L-methionine
-
 ?
3.5.1.31 N-formyl-L-methionine + H2O
-
 Bos taurus formate + L-methionine
-
 ?
3.5.1.31 N-formyl-leucine + H2O at 0.8-12% of the activity with N-formyl-methionine, depending on tissue Rattus norvegicus formate + leucine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.31 additional information
-
 27% more active with phosphate than with Tris-Cl- buffer Rattus norvegicus
3.5.1.31 7.4
-
-
 Gallus gallus
3.5.1.31 7.4
-
-
 Rattus norvegicus
3.5.1.31 7.4
-
-
 Sus scrofa
3.5.1.31 7.4
-
-
 Bos taurus