Literature summary extracted from

Schlein, Y.; Jacobosn, R.L.; Shlomai, J.
Chitinase secreted by Leishmania in the sandfly vector (1991), Proc. R. Soc. Lond. B Biol. Sci., 245, 121-126.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.2.1.14	54.7	-	p-nitrophenyl beta-D-N,N'-diacetylchitobiose	-	Leishmania major
3.2.1.52	18.8	-	p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside	-	Leishmania major

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.2.1.14	extracellular	-	Leishmania major	-	-
3.2.1.52	extracellular	-	Leishmania major	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.2.1.14	Crithidia fasciculata	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Herpetomonas muscarum	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Leishmania braziliensis	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Leishmania donovani	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Leishmania infantum	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Leishmania major	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Leptomonas seymouri	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.14	Trypanosoma lewisi	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Crithidia fasciculata	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Herpetomonas muscarum	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Leishmania braziliensis	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Leishmania donovani	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Leishmania infantum	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Leishmania major	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Leptomonas seymouri	-	sandfly, Phlebotomus papatasi, infected	-
3.2.1.52	Trypanosoma lewisi	-	sandfly, Phlebotomus papatasi, infected	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.2.1.14	promastigote	-	Leishmania major	-
3.2.1.52	promastigote	-	Leishmania major	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.2.1.14	p-nitrophenyl-beta-D-N,N'-diacetylchitobiose + H2O	-	Leishmania major	p-nitrophenol + N,N'-diacetylchitobiose	-	?
3.2.1.52	p-nitrophenyl-beta-2-acetamido-2-deoxy-D-glucopyranoside + H2O	-	Leishmania major	2-acetamido-2-deoxy-D-glucose + p-nitrophenol	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
3.2.1.14	4.5	-	-	Leishmania major
3.2.1.52	5	-	-	Leishmania major

pH Range

EC Number	pH Minimum	pH Maximum	Comment	Organism
3.2.1.14	4.5	5.5	-	Leishmania major
3.2.1.52	4.5	5.5	-	Leishmania major

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Release 2023.1 (January 2023)