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Literature summary extracted from

  • Bobik, T.A.; Olson, K.D.; Noll, K.M.; Wolfe, R.S.
    Evidence that the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate is a product of the methylreductase reaction in Methanobacterium (1987), Biochem. Biophys. Res. Commun., 149, 455-460.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.8.4.1 Ti(III) citrate nickel tetrahydrocorphin Methanothermobacter thermautotrophicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.4.1 coenzyme M
-
Methanothermobacter thermautotrophicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.4.1 300000
-
-
Methanothermobacter thermautotrophicus

Organism

EC Number Organism UniProt Comment Textmining
2.8.4.1 Methanothermobacter thermautotrophicus
-
ATCC 29096
-
2.8.4.1 Methanothermobacter thermautotrophicus
-
deltaH
-
2.8.4.1 Methanothermobacter thermautotrophicus DELTAH
-
deltaH
-

Storage Stability

EC Number Storage Stability Organism
2.8.4.1 -20°C, 50 mM potassium PIPES buffer, pH 6.2, 15 mM MgCl2, 10 mM 2-mercaptoethanol Methanothermobacter thermautotrophicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.4.1 methyl-coenzyme M + coenzyme B
-
Methanothermobacter thermautotrophicus methane + CoM-S-S-CoB
-
?
2.8.4.1 methyl-coenzyme M + coenzyme B
-
Methanothermobacter thermautotrophicus DELTAH methane + CoM-S-S-CoB
-
?

Subunits

EC Number Subunits Comment Organism
2.8.4.1 hexamer alpha2,beta2,gamma2 Methanothermobacter thermautotrophicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.4.1 60
-
assay Methanothermobacter thermautotrophicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.8.4.1 F-430 2 mol coenzyme F-430/mol enzyme Methanothermobacter thermautotrophicus