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Literature summary extracted from

  • MacLeod, R.M.; Farkas, W.; Fridovich, I.; Handler, P.
    Purification and properties of hepatic sulfite oxidase (1961), J. Biol. Chem., 236, 1841-1846.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.8.3.1 glycine
-
 Bos taurus
1.8.3.1 glycine
-
 Canis lupus familiaris

General Stability

EC Number General Stability Organism
1.8.3.1 trypsin inactivates Rattus norvegicus
1.8.3.1 trypsin inactivates Bos taurus
1.8.3.1 trypsin inactivates Canis lupus familiaris

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.3.1 Ag+
-
 Bos taurus
1.8.3.1 Ag+
-
 Canis lupus familiaris
1.8.3.1 Ag+
-
 Rattus norvegicus
1.8.3.1 heavy metal ions
-
 Bos taurus
1.8.3.1 heavy metal ions
-
 Canis lupus familiaris
1.8.3.1 heavy metal ions
-
 Rattus norvegicus
1.8.3.1 Hg2+
-
 Bos taurus
1.8.3.1 Hg2+
-
 Canis lupus familiaris
1.8.3.1 Hg2+
-
 Rattus norvegicus
1.8.3.1 additional information not inhibitory: CN- Bos taurus
1.8.3.1 additional information not inhibitory: CN- Rattus norvegicus
1.8.3.1 p-chloromercuribenzoate
-
 Bos taurus
1.8.3.1 p-chloromercuribenzoate
-
 Canis lupus familiaris
1.8.3.1 p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.3.1 additional information
-
 additional information
-
 Rattus norvegicus
1.8.3.1 additional information
-
 additional information
-
 Bos taurus
1.8.3.1 additional information
-
 additional information
-
 Canis lupus familiaris

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.3.1 mitochondrion
-
 Rattus norvegicus 5739
-
1.8.3.1 mitochondrion
-
 Bos taurus 5739
-
1.8.3.1 mitochondrion
-
 Canis lupus familiaris 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.8.3.1 Bos taurus
-
-
-
1.8.3.1 Canis lupus familiaris
-
-
-
1.8.3.1 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.3.1
-
 Rattus norvegicus
1.8.3.1
-
 Bos taurus
1.8.3.1
-
 Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.3.1 brain low activity Rattus norvegicus
-
1.8.3.1 brain low activity Bos taurus
-
1.8.3.1 brain low activity Canis lupus familiaris
-
1.8.3.1 heart
-
 Rattus norvegicus
-
1.8.3.1 heart
-
 Bos taurus
-
1.8.3.1 heart
-
 Canis lupus familiaris
-
1.8.3.1 kidney
-
 Rattus norvegicus
-
1.8.3.1 kidney
-
 Bos taurus
-
1.8.3.1 kidney
-
 Canis lupus familiaris
-
1.8.3.1 lung low activity Rattus norvegicus
-
1.8.3.1 lung low activity Bos taurus
-
1.8.3.1 lung low activity Canis lupus familiaris
-
1.8.3.1 additional information activity in tissues and cells Rattus norvegicus
-
1.8.3.1 spleen low activity Rattus norvegicus
-
1.8.3.1 spleen low activity Bos taurus
-
1.8.3.1 spleen low activity Canis lupus familiaris
-
1.8.3.1 testis low activity Rattus norvegicus
-
1.8.3.1 testis low activity Bos taurus
-
1.8.3.1 testis low activity Canis lupus familiaris
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.8.3.1 additional information
-
 comparison of activity in different cells and tissues Rattus norvegicus
1.8.3.1 additional information
-
 activity in different organelles Rattus norvegicus
1.8.3.1 additional information
-
 activity in different organelles Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.3.1 sulfite + H2O + A
-
 Rattus norvegicus SO42- + AH2
-
 ?
1.8.3.1 sulfite + H2O + A
-
 Bos taurus SO42- + AH2
-
 ?
1.8.3.1 sulfite + H2O + A
-
 Canis lupus familiaris SO42- + AH2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.8.3.1 8.5
-
-
 Bos taurus
1.8.3.1 8.5
-
-
 Canis lupus familiaris

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.8.3.1 7 9.5 quite stable, but unstable below pH 7.0 Rattus norvegicus
1.8.3.1 7 9.5 quite stable, but unstable below pH 7.0 Bos taurus
1.8.3.1 7 9.5 quite stable, but unstable below pH 7.0 Canis lupus familiaris