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Literature summary extracted from

  • Kitajima-Ihara, T.; Yagi, T.
    Rotenone-insensitive internal NADH-quinone oxidoreductase of saccharomyces cerevisiae mitochondria: the enzyme expressed in Escherichia coli acts as a member of the respiratory chain in the host cells (1998), FEBS Lett., 421, 37-40.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.1.1.2 the enzyme overexpressed in Escherichia coli acts as a member of the respiratory chain in the host cell Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.2 KCN
-
 Saccharomyces cerevisiae
7.1.1.2 NADH
-
 Saccharomyces cerevisiae
7.1.1.2 rotenone rotenone-insensitive enzyme Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.2 mitochondrial membrane
-
 Saccharomyces cerevisiae 31966
-
7.1.1.2 mitochondrion membrane Saccharomyces cerevisiae 5739
-

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.2 Saccharomyces cerevisiae
-
 rotenone-insensitive enzyme
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.2 NADH + ubiquinone
-
 Saccharomyces cerevisiae NAD+ + ubiquinol
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.2 FAD enzyme contains FAD Saccharomyces cerevisiae
7.1.1.2 NADH
-
 Saccharomyces cerevisiae

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
7.1.1.2 0.0083
-
 NADH
-
 Saccharomyces cerevisiae